OncoMatch

OncoMatch/Clinical Trials/NCT04874038

Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)

Is NCT04874038 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies Lidocaine 20mg/ml for post-mastectomy pain syndrome.

Phase 3RecruitingUniversity Health Network, TorontoNCT04874038Data as of Jun 2026Location: Canada · Nepal · Nigeria

Treatment: Lidocaine 20mg/mlPhase III, international multicentre, parallel group, blinded, 1:1 randomized controlled trial to determine the effect of an intraoperative intravenous lidocaine infusion on reducing the development of persistent pain 3-months after breast cancer surgery.

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Extracted eligibility criteria

Treatments studied

Other

Lidocaine 20mg/ml

Cancer type

Breast Carcinoma

Biomarker criteria

Allowed: BRCA1 any tested

including prophylactic surgery (e.g., family history or BRCA gene mutation)

Allowed: BRCA2 any tested

including prophylactic surgery (e.g., family history or BRCA gene mutation)

Demographics

Ages ≤ 100

Prior therapy

Cannot have received: breast surgery

Previous breast surgery within 6 months of index surgery

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT04874038 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior breast surgery disqualifies patients from enrollment.

Is there an age limit?

Yes. Patients must be 100 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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