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OncoMatch/Clinical Trials/NCT04830267

The Efficacy of Camrelizumab Plus Stereotactic Body Radiotherapy in R/M NPC

Is NCT04830267 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Camrelizumab for nasopharyngeal carcinoma.

Phase 2RecruitingChongqing University Cancer HospitalNCT04830267Data as of May 2026

Treatment: CamrelizumabCamrelizumab is an antibody targeting programmed death receptor 1 (PD-1) and its ligand programmed death-ligand 1 (PD- L1) that is designed to boost the immune system. It does this by allowing immune cells to fight the cancer. Stereotactic body radiotherapy is a potential immunostimulatory therapy that may amplify antitumor response when combined with camrelizumab.

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Extracted eligibility criteria

Cancer type

Head and Neck Squamous Cell Carcinoma

Disease stage

Metastatic disease required

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Lab requirements

Blood counts

WBC ≥ 2 K/microliter; Neutrophils ≥ 1.5 K/microliter; Platelets ≥ 100 K/microliter; Hemoglobin ≥ 9.0 g/deciliter

Kidney function

Serum Creatinine ≤ 1.5 x ULN or creatinine clearance > 40ml/min using the Cockcroft-Gault formula

Liver function

AST/ALT ≤ 3 x ULN; Total bilirubin <1.5 x ULN (except subjects with Gilbert Syndrome who can have total bilirubin <3.0 mg/deciliter)

Screening laboratory values must meet the following criteria (using CTCAE v4.0): WBC ≥ 2 K/microliter Neutrophils ≥ 1.5 K/microliter Platelets ≥ 100 K/microliter Hemoglobin ≥ 9.0 g/deciliter Serum Creatinine ≤ 1.5 x ULN or creatinine clearance > 40ml/min ... AST/ALT ≤ 3 x ULN Total bilirubin <1.5 x ULN (except subjects with Gilbert Syndrome who can have total bilirubin <3.0 mg/deciliter).

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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