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OncoMatch/Clinical Trials/NCT04813705

18F-FDG PET/CT Guided Reduced-dose Radiotherapy for Nasopharyngeal Carcinoma

Is NCT04813705 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Chemotherapy for nasopharyngeal carcinoma.

Phase 2RecruitingTaizhou HospitalNCT04813705Data as of Jun 2026Location: China

Treatment: ChemotherapyThe purpose of this study is to explore whether 18F-FDG PET/CT guided reduced-dose radiotherapy would maintain survival outcomes in nasopharyngeal carcinoma (NPC) patients.

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Extracted eligibility criteria

Treatments studied

Other

Chemotherapy

Cancer type

Head and Neck Squamous Cell Carcinoma

Disease stage

Required: Stage I, II, III, IVA

Demographics

Ages ≤ 80

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: radiation therapy

Exception: non-melanomatous skin cancers outside intended RT treatment volume

History of previous radiotherapy (except for non-melanomatous skin cancers outside intended RT treatment volume).

Cannot have received: chemotherapy

Prior chemotherapy ... to primary tumor or nodes.

Cannot have received: surgery

Exception: diagnostic

Prior ... surgery (except diagnostic) to primary tumor or nodes.

Lab requirements

Blood counts

HGB≥90 g/L, ANC≥1.5×10^9/L, PLT≥80×10^9/L.

Kidney function

CCR≥60ml/min or Cr<1.5×ULN.

Liver function

ALT, AST <2.5 fold of ULN; TBIL <2.0×ULN.

HGB≥90 g/L,ANC≥1.5×10^9 /L,PLT≥80×10^9 /L. ALT,AST<2.5 fold of ULN;TBIL<2.0×ULN. CCR≥60ml/min or Cr<1.5×ULN.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT04813705 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

What disease stage is eligible?

Stage I or II or III or IVA is required.

Is there an age limit?

Yes. Patients must be 80 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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