OncoMatch/Clinical Trials/NCT04778839
Study of Paclitaxel Micelles for Injection in Chinese Patients With Advanced Solid Tumors.
Is NCT04778839 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1 trial studies multiple treatments including Paclitaxel and Paclitaxel Micelles for for advanced solid tumors.
Treatment: Paclitaxel · Paclitaxel Micelles for — A Phase I Study of Dose Escalation and Dose Expansion To Evaluate the Safety、Tolerability、Pharmacokinetics and Preliminary Efficacy of Paclitaxel Micelles for Injection in Chinese Patients With Advanced Solid Tumor.
Check if I qualifyExtracted eligibility criteria
Treatments studied
Chemotherapy
Cancer type
Tumor Agnostic
Performance status
ECOG 0–2(Ambulatory, capable of self-care)
Demographics
Prior therapy
Cannot have received: paclitaxel
Exception: unless not resistant
Patients who had been treated with paclitaxel and were determined by the researchers to be resistant
Lab requirements
Blood counts
Hb ≥ 90 g/L, ANC ≥ 1.5×10^9/L, PLT ≥ 100×10^9/L; no blood transfusion, blood products, or hematopoietic growth factors within 14 days prior to screening
Kidney function
creatinine ≤ 1.5×ULN and CL ≥ 60 mL/min
Liver function
ALT or AST ≤ 2.5×ULN (for patients with hepatic metastases, ALT or AST ≤ 5 × ULN); TBIL ≤ 1.5×ULN
Cardiac function
LVEF ≥ 50%
No severe hematopoietic abnormalities(no blood transfusion, no blood products, no granulocyte colony-stimulating factor, platelet stimulating factor, or other hematopoietic growth factors were corrected within 14 days prior to the screening phase laboratory examination):Hb≥90g/L , ANC≥1.5×109/L , PLT≥100×109/L. No serious organic disease of heart, liver or kidney:LVEF≥50% ; ALT(Alanine aminotransferase) or AST(Aspartate transaminase)≤2.5×upper limit of normal(ULN)(for patients with hepatic metastases, ALT or AST≤5 × ULN); TBIL(Total bilirubin)≤1.5×ULN; creatinine≤1.5×ULN and CL≥ 60 mL/min
Structured fields extracted by AI. May contain errors — verify against the official protocol.
Frequently asked questions
Is NCT04778839 currently recruiting?
Yes, this trial is currently recruiting patients.
Are there prior therapy exclusions?
Yes. Prior paclitaxel disqualifies patients from enrollment.
Is there an age limit?
Yes. Patients must be 70 years or younger.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualify