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OncoMatch/Clinical Trials/NCT04772456

Hyperpolarized 13C-pyruvate Metabolic MRI With Infiltrating Gliomas

Is NCT04772456 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies Hyperpolarized 13C-Pyruvate for glioma.

Phase 1RecruitingUniversity of Maryland, BaltimoreNCT04772456Data as of May 2026

Treatment: Hyperpolarized 13C-PyruvateThe purpose of this study is to examine the safety and feasibility of performing hyperpolarized metabolic MRI in the diagnosis of brain tumor. This study will also assess the accuracy of hyperpolarized metabolic MRI to diagnose intermediate to patients with infiltrating gliomas and examine the added utility of metabolic MRI over standard MRI imaging The FDA is allowing the use of hyperpolarized \[1-13C\] pyruvate (HP 13C-pyruvate) in this study. Up to 5 patients may take part in this study at the University of Maryland, Baltimore (UMB).

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Extracted eligibility criteria

Cancer type

Glioblastoma

Lab requirements

Kidney function

sufficient to receive iv contrast

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Rosy Njonkou Tchoquessi · Baltimore, Maryland

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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