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OncoMatch/Clinical Trials/NCT04726241

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

Is NCT04726241 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies non-drug interventions for acute lymphoblastic leukemia.

Phase 1/2RecruitingPedAL BCU, LLCNCT04726241Data as of May 2026

This study aims to use clinical and biological characteristics of acute leukemias to screen for patient eligibility for available pediatric leukemia sub-trials. Testing bone marrow and blood from patients with leukemia that has come back after treatment or is difficult to treat may provide information about the patient's leukemia that is important when deciding how to best treat it, and may help doctors find better ways to diagnose and treat leukemia in children, adolescents, and young adults.

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Extracted eligibility criteria

Cancer type

Acute Lymphoblastic Leukemia

Acute Myeloid Leukemia

Myelodysplastic Syndrome

Biomarker criteria

Required: KMT2A (MLL) rearrangement

Required: KMT2A (MLL) wild-type

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Children's Hospital of Alabama · Birmingham, Alabama
  • USA Health Strada Patient Care Center · Mobile, Alabama
  • Providence Alaska Medical Center · Anchorage, Alaska
  • Banner Children's at Desert · Mesa, Arizona
  • Phoenix Childrens Hospital · Phoenix, Arizona

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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