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OncoMatch/Clinical Trials/NCT04700527

The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study

Is NCT04700527 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1/2 trial studies multiple treatments including Short Chain Fatty Acid and Tapioca Flour for toxicity.

Phase 1/2RecruitingUNC Lineberger Comprehensive Cancer CenterNCT04700527Data as of Jun 2026

Treatment: Short Chain Fatty Acid · Tapioca FlourThe purpose of this study is to assess and compare GI toxicity from RT between subjects who receive therapeutic SCFA and those who receive placebo, in hopes of identifying a safe, low-cost therapeutic to reduce GI toxicity from therapeutic or environmental radiation.

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Extracted eligibility criteria

Treatments studied

Other

Short Chain Fatty AcidTapioca Flour

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Cannot have received: abdominopelvic radiation therapy

Lab requirements

Kidney function

Creatinine clearance < 50 mL/min [excluded]

Cardiac function

Congestive heart failure [excluded]

Creatinine clearance < 50 mL/min; Congestive heart failure [excluded]

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Flora Danquah · Chapel Hill, North Carolina

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT04700527 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior abdominopelvic radiation therapy disqualifies patients from enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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