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OncoMatch/Clinical Trials/NCT04691817

Tocilizumab and Atezolizumab in Adults With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Refractory to 1st Line Immune Checkpoint Inhibitor-Based Therapy

Is NCT04691817 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies multiple treatments including Atezolizumab and Tocilizumab for lung cancer, nonsmall cell.

Phase 1/2RecruitingAbramson Cancer Center at Penn MedicineNCT04691817Data as of May 2026

Treatment: Atezolizumab · TocilizumabThis is a research study to evaluate the safety and effectiveness of tocilizumab in combination with atezolizumab to treat non-small cell lung cancer.

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Extracted eligibility criteria

Cancer type

Non-Small Cell Lung Carcinoma

Disease stage

Required: Stage IV

Metastatic disease required

Advanced non-squamous NSCLC (Stage IV or recurrent after initial curative intent therapy)

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Min 1 prior line

Must have received: checkpoint inhibitor — immediately prior to enrollment

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Abramson Cancer Center of the University of Pennsylvania · Philadelphia, Pennsylvania

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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