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OncoMatch/Clinical Trials/NCT04689048

Assess Use of 18F-Fluciclovine for Patients With Large Brain Metastases Treated With Staged Stereotactic Radiosurgery

Is NCT04689048 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies 18F fluciclovine for brain metastases, adult.

Phase 1RecruitingBaptist Health South FloridaNCT04689048Data as of May 2026

Treatment: 18F fluciclovineThe spread of cancer to the brain is referred to as brain metastases. Brain metastases are a common complication of cancer. This study is being done to determine whether the use of a new imaging agent, 18F-fluciclovine, is able to detect which patients are responding to radiation therapy. In addition, this study will look at the changes of the treated brain metastases using this imaging agent over time.

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Extracted eligibility criteria

Cancer type

Glioblastoma

Disease stage

Metastatic disease required

Confirmed diagnosis of brain metastases with at least one untreated lesion >2 cm in maximum diameter

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Cannot have received: whole-brain radiation therapy

Prior whole-brain radiation therapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Miami Cancer Institute · Miami, Florida

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