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OncoMatch/Clinical Trials/NCT04683653

Study of Pelvic Hypofractionated Radiotherapy in Endometrial Cancer

Is NCT04683653 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies non-drug interventions for endometrial cancer.

Phase 1/2RecruitingUniversity of ChicagoNCT04683653Data as of May 2026

This study will investigate if a shorter treatment course (known as "hypofractionation") for pelvic radiation is safe for women with endometrial cancer. Doctors leading the study will also determine the safest and most tolerable dose of shortened radiation (hypofractionation) used to treat women in this study. Because this study will shorten the radiation course typically used to treat endometrial cancer, each daily treatment given to women in this study will be slightly higher than normal to ensure that the total radiation dose they receive is still effective and similar to the radiation dose they would receive if they were not participating in this study (standard treatment).

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Extracted eligibility criteria

Cancer type

Endometrial Cancer

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Must have received: surgery — definitive

Cannot have received: radiation therapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Winship Cancer Institute, Emory University · Atlanta, Georgia
  • University of Illinois at Chicago (UIC) · Chicago, Illinois
  • University of Chicago · Chicago, Illinois
  • MD Anderson Cancer Center · Houston, Texas
  • Huntsman Cancer Institute · Salt Lake City, Utah

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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