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OncoMatch/Clinical Trials/NCT04641247

A Long-term Treatment Extension Study of Niraparib in Participants Who Completed a Prior GlaxoSmithKline/TESARO-sponsored Niraparib Study

Is NCT04641247 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Niraparib for ovarian neoplasms.

Phase 2RecruitingGlaxoSmithKlineNCT04641247Data as of May 2026

Treatment: NiraparibThis is a global extension study to provide continued access to niraparib and further characterize the long-term safety of niraparib treatment in participants who are currently receiving treatment with niraparib within GlaxoSmithKline/TESARO-sponsored studies (NCT01847274, NCT02354586, NCT01905592, NCT03308942, NCT02657889) that has fulfilled the requirements for the primary objective.

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Extracted eligibility criteria

Cancer type

Ovarian Cancer

Breast Carcinoma

Prior therapy

Must have received: PARP inhibitor (niraparib) — parent GlaxoSmithKline/TESARO-sponsored study

currently receiving treatment with niraparib (as monotherapy or in combination) in a GlaxoSmithKline/TESARO-sponsored study that has fulfilled the requirements for the primary objective

Cannot have received: PARP inhibitor (niraparib)

has been permanently discontinued from niraparib treatment in the parent study for any reason

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • GSK Investigational Site · Tucson, Arizona
  • GSK Investigational Site · Encinitas, California
  • GSK Investigational Site · Los Angeles, California
  • GSK Investigational Site · Whittier, California
  • GSK Investigational Site · Jacksonville, Florida

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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