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OncoMatch/Clinical Trials/NCT04615143

Tislelizumab or Tislelizumab Combined With Lenvatinib Neo-adjuvant Treatment for Resectable RHCC

Is NCT04615143 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments including Tislelizumab and Tislelizumab combined with Levatinib for recurrent hepatocellular carcinoma.

Phase 2RecruitingSun Yat-sen UniversityNCT04615143Data as of May 2026

Treatment: Tislelizumab · Tislelizumab combined with LevatinibThis non-randomized phase II clinical trial aimed to explore the efficacy and safety of Tislelizumab or Tislelizumab combined with Lenvatinib as neoadjuvant treatment for resectable RHCC patients

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Extracted eligibility criteria

Cancer type

Hepatocellular Carcinoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Must have received: curative ablation

Diagnosed as recurrent hepatocellular carcinoma after curative treatment

Cannot have received: transarterial chemoembolization

Previously received any transarterial chemoembolization

Cannot have received: immunotherapy

Previously received any...immune therapy

Cannot have received: other local or systemic liver cancer treatments

Exception: except for curative ablation

Previously received any...other local or systemic liver cancer treatments, except for curative ablation

Lab requirements

Liver function

child-pugh score 5-7

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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