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OncoMatch/Clinical Trials/NCT04615143

Tislelizumab or Tislelizumab Combined With Lenvatinib Neo-adjuvant Treatment for Resectable RHCC

Is NCT04615143 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments including Tislelizumab and Tislelizumab combined with Levatinib for recurrent hepatocellular carcinoma.

Phase 2RecruitingSun Yat-sen UniversityNCT04615143Data as of Jun 2026Location: China

Treatment: Tislelizumab · Tislelizumab combined with LevatinibThis non-randomized phase II clinical trial aimed to explore the efficacy and safety of Tislelizumab or Tislelizumab combined with Lenvatinib as neoadjuvant treatment for resectable RHCC patients

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Extracted eligibility criteria

Treatments studied

Immunotherapy

Tislelizumab

Targeted therapy

Tislelizumab combined with Levatinib

Cancer type

Hepatocellular Carcinoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 75

Prior therapy

Must have received: curative ablation

Diagnosed as recurrent hepatocellular carcinoma after curative treatment

Cannot have received: transarterial chemoembolization

Previously received any transarterial chemoembolization

Cannot have received: immunotherapy

Previously received any...immune therapy

Cannot have received: other local or systemic liver cancer treatments

Exception: except for curative ablation

Previously received any...other local or systemic liver cancer treatments, except for curative ablation

Lab requirements

Liver function

child-pugh score 5-7

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT04615143 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior transarterial chemoembolization, immunotherapy, other local or systemic liver cancer treatments disqualifies patients from enrollment.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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