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OncoMatch/Clinical Trials/NCT04540107

Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma

Is NCT04540107 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies Hyperpolarized Carbon C 13 Pyruvate for recurrent world health organization (who) grade ii glioma.

Phase 1RecruitingSusan ChangNCT04540107Data as of May 2026

Treatment: Hyperpolarized Carbon C 13 PyruvateThis trial studies how well serial magnetic resonance (MR) imaging and MR spectroscopic imaging work in characterizing lower grade glioma. Diagnostic procedures, such as MR imaging and MR spectroscopic imaging, may detect serial changes in lower grade glioma. This study may help researchers learn more about practical ways of evaluating and standardizing treatment in patients with brain tumors.

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Extracted eligibility criteria

Cancer type

Glioblastoma

Disease stage

Required: Stage II, III (WHO)

Grade: IIIII (WHO)

WHO Grade II Glioma; WHO Grade III Glioma

Lab requirements

Kidney function

creatinine < 1.5 mg/dL before imaging

Cardiac function

No NYHA grade II or greater congestive heart failure; no history of myocardial infarction or unstable angina within 12 months prior to study enrollment

adequate renal function (creatinine < 1.5 mg/dL) before imaging ... must not have NYHA grade II or greater congestive heart failure ... must not have history of myocardial infarction or unstable angina within 12 months prior to study enrollment

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of California, San Francisco · San Francisco, California

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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