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OncoMatch/Clinical Trials/NCT04510636

Study of Pembrolizumab With Bendamustine in Hodgkin Lymphoma

Is NCT04510636 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments including Pembrolizumab and Bendamustine Hydrochloride for classical hodgkin lymphoma.

Phase 2RecruitingUniversity Health Network, TorontoNCT04510636Data as of May 2026

Treatment: Pembrolizumab · Bendamustine HydrochlorideThis is a phase 2 open-label study to test the safety and effectiveness of combining pembrolizumab and bendamustine in patients with relapsed (cancer that has come back or started getting worse) or refractory (cancer that is not responding or has stopped responding to treatment) Hodgkin lymphoma.

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Extracted eligibility criteria

Cancer type

Hodgkin Lymphoma

Tumor Agnostic

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Min 1 prior line

Must have received: anthracycline — first line

Must have received at least standard first line chemotherapy for classical Hodgkin Lymphoma, containing an anthracycline

Cannot have received: bendamustine

Patient has received prior treatment with bendamustine, either as monotherapy or as part of a combination regimen

Cannot have received: allogeneic hematopoietic stem cell transplant

Patient has undergone prior allogeneic hematopoietic stem cell transplant

Lab requirements

Blood counts

adequate organ and bone marrow function

Kidney function

adequate organ and bone marrow function

Liver function

adequate organ and bone marrow function

Demonstrate adequate organ and bone marrow function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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