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OncoMatch/Clinical Trials/NCT04506008

Hypofractionated Radiotherapy Followed by Surgical Resection in the Treatment of Soft Tissue Sarcomas

Is NCT04506008 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies non-drug interventions for soft tissue sarcomas.

Phase 2RecruitingVanderbilt-Ingram Cancer CenterNCT04506008Data as of May 2026

The trial will use neoadjuvant hypofractionated radiotherapy followed by surgical resection in the treatment for soft tissue sarcoma. It will allow patients to be treated over a shorter course (5 or 15 days of radiation) compared to the traditional 5 week regimen. It is proposed that this will be possible without increasing the risk of wound complication or local recurrence compared with a traditional 5 week course of pre-operative radiation.

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Extracted eligibility criteria

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Cannot have received: radiation therapy

Exception: to the same area to be irradiated

History of prior radiation to the same area to be irradiated

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Vanderbilt-Ingram Cancer Center · Nashville, Tennessee

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