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OncoMatch/Clinical Trials/NCT04503265

A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

Is NCT04503265 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1/2 trial studies multiple treatments including AMXI-5001:Dose Escalation Phase I and AMXI-5001:Dose Expansion Phase II for advanced malignant neoplasm.

Phase 1/2RecruitingAtlasMedx, IncorporatedNCT04503265Data as of Jun 2026

Treatment: AMXI-5001:Dose Escalation Phase I · AMXI-5001:Dose Expansion Phase IIATLAS-101 is a Phase I/II clinical trial of AMXI-5001 in adult participants with advanced malignancies who have previously failed other therapies. The study has two phases. The purpose of Phase I (Dose Escalation) is to confirm the appropriate treatment dose and Phase II (Dose Expansion) is to characterize the safety and efficacy of AMXI-5001.

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Extracted eligibility criteria

Treatments studied

Other

AMXI-5001:Dose Escalation Phase IAMXI-5001:Dose Expansion Phase II

Cancer type

Tumor Agnostic

Breast Carcinoma

Ovarian Cancer

Prostate Cancer

Pancreatic Cancer

Disease stage

Required: Stage IV

Metastatic disease required

advanced or metastatic malignancy

Performance status

ECOG 0–1(Restricted strenuous activity)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of California, Los Angles (UCLA) Department of Medicine - Hematology/Oncology · Los Angeles, California
  • Johns Hopkins · Baltimore, Maryland
  • SCRI Oncology Partners · Nashville, Tennessee
  • The University of Texas MD Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT04503265 currently recruiting?

Yes, this trial is currently recruiting patients.

What disease stage is eligible?

Stage IV is required (metastatic disease required).

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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