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OncoMatch/Clinical Trials/NCT04503265

A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

Is NCT04503265 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies multiple treatments including AMXI-5001:Dose Escalation Phase I and AMXI-5001:Dose Expansion Phase II for advanced malignant neoplasm.

Phase 1/2RecruitingAtlasMedx, IncorporatedNCT04503265Data as of May 2026

Treatment: AMXI-5001:Dose Escalation Phase I · AMXI-5001:Dose Expansion Phase IIATLAS-101 is a Phase I/II clinical trial of AMXI-5001 in adult participants with advanced malignancies who have previously failed other therapies. The study has two phases. The purpose of Phase I (Dose Escalation) is to confirm the appropriate treatment dose and Phase II (Dose Expansion) is to characterize the safety and efficacy of AMXI-5001.

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Extracted eligibility criteria

Cancer type

Tumor Agnostic

Breast Carcinoma

Ovarian Cancer

Prostate Cancer

Pancreatic Cancer

Disease stage

Required: Stage IV

Metastatic disease required

advanced or metastatic malignancy

Performance status

ECOG 0–1(Restricted strenuous activity)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of California, Los Angles (UCLA) Department of Medicine - Hematology/Oncology · Los Angeles, California
  • Johns Hopkins · Baltimore, Maryland
  • SCRI Oncology Partners · Nashville, Tennessee
  • The University of Texas MD Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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