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OncoMatch/Clinical Trials/NCT04468841

Measuring Cell-Free DNA (cfDNA) Levels in People With Follicular Lymphoma

Is NCT04468841 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1 trial studies non-drug interventions for follicular lymphoma.

Phase 1RecruitingMemorial Sloan Kettering Cancer CenterNCT04468841Data as of Jun 2026

The researchers are doing this study to measure and test cell-free DNA (cfDNA) in the blood before, during, and after first-line treatment for follicular lymphoma. They will look at whether cfDNA levels are related to a person's response to the usual first-line treatment for follicular lymphoma. Researchers also want to understand how different genetic changes in follicular lymphoma relate to a person's response to the usual first-line treatment.

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Extracted eligibility criteria

Cancer type

Non-Hodgkin Lymphoma

Prior therapy

Max 1 prior line

Cannot have received:

Exception: retrospective cohort of long-term survivors of FL [i.e. >10 years out from frontline treatment]

Patients receiving second or greater line of therapy (except in retrospective cohort of long-term survivors of FL [i.e. >10 years out from frontline treatment])

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Memorial Sloan Kettering Monmouth (All protocol activities) · Middletown, New Jersey
  • Memorial Sloan Kettering Bergen (All protocol Activities) · Montvale, New Jersey
  • Memorial Sloan Kettering Commack (All Protocol Activities) · Commack, New York
  • Memorial Sloan Kettering Westchester (All Protocol Activities) · Harrison, New York
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities) · New York, New York

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT04468841 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior disqualifies patients from enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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