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OncoMatch/Clinical Trials/NCT04402151

Study of PSMA PET/MR Guided Stereotactic Body Radiation Therapy With Simultaneous Integrated Boost (SBRT-SIB) for High-Intermediate and High Risk Prostate Cancer

Is NCT04402151 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies PSMA PET/MR - Gallium-68 labeled PSMA-HBED-CC for prostate cancer.

Phase 2RecruitingWeill Medical College of Cornell UniversityNCT04402151Data as of May 2026

Treatment: PSMA PET/MR - Gallium-68 labeled PSMA-HBED-CCThis is a single-arm Phase II clinical trial assessing the clinical efficacy of prostate specific membrane antigen (PSMA) PET/MR guided MR-LINAC based SBRT-SIB with planned accrual of 50 patients.

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Extracted eligibility criteria

Cancer type

Prostate Cancer

Disease stage

Required: Stage T2C OR GREATER, T2B (UNFAVORABLE INTERMEDIATE RISK)

Excluded: Stage METASTATIC DISEASE, PELVIC LYMPH NODES

Grade: Gleason 8-10tertiary component 5Gleason 4+3=7Gleason 7 (Gleason)

Gleason 8-10 or tertiary component 5 disease and/or PSA of 20 ng/ml or greater and/or Tumor stage of T2c or greater; OR Unfavorable intermediate risk (Gleason 4+3=7, >50% of cores involved, or 2 or more intermediate risk factors which include Gleason 7 disease, PSA 10-20, or T2b disease)

Prior therapy

Cannot have received: abiraterone (abiraterone)

Patients on or intending to take abiraterone will be excluded

Cannot have received: radiation therapy

history of prior radiation to the prostate

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Weill Cornell Medicine · New York, New York

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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