OncoMatch

OncoMatch/Clinical Trials/NCT04378647

BREntuximab Vedotin in SEcond LIne Therapy BEfore Transplant

Is NCT04378647 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments including Induction with Brentuximab vedotin (BV) and Induction without Brentuximab Vedotin for hodgkin lymphoma, adult.

Phase 2RecruitingGrupo Español de Linfomas y Transplante Autólogo de Médula ÓseaNCT04378647Data as of May 2026

Treatment: Induction with Brentuximab vedotin (BV) · Induction without Brentuximab Vedotin · Consolidation with Brentuximab VedotinA Randomized Phase IIb Study, Evaluating Efficacy of Salvage Therapy with Brentuximab Vedotin-ESHAP vs ESHAP in Patients with Relapsed / Refractory Classical Hodgkin's Lymphoma, Followed by Brentuximab Vedotin Consolidation (instead of Autologous Hematopoietic Stem Cell Transplantation) in Those who Attained a Metabolic Complete Remission after Salvage Therapy

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Extracted eligibility criteria

Cancer type

Hodgkin Lymphoma

Biomarker criteria

Required: CD30 positive (positive)

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Cannot have received: brentuximab vedotin (brentuximab vedotin)

Prior treatment with brentuximab vedotin

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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