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OncoMatch/Clinical Trials/NCT04371224

NaliCap (Irinotecan Liposome (Nal-IRI)/Capecitabine) vs. NAPOLI (Nal-IRI/5-FU/LV) ) in Advanced Pancreatic Cancer

Is NCT04371224 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments including Irinotecan Liposomal and Capecitabine for pancreatic cancer.

Phase 2RecruitingSeoul National University HospitalNCT04371224Data as of May 2026

Treatment: Irinotecan Liposomal · Capecitabine · 5-fluorouracil · LeucovorinThis is an open label, randomized phase 2 study of NaliCap (irinotecan liposome/Capecitabine) compared to NAPOLI (irinotecan liposome/5-FU/LV) in gemcitabine-pretreated advanced pancreatic cancer patients.

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Extracted eligibility criteria

Cancer type

Pancreatic Cancer

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Min 1 prior line

Must have received: gemcitabine (gemcitabine) — advanced pancreatic cancer

Gemcitabine-pretreated for advanced pancreatic cancer

Cannot have received: investigational product

Participation in another clinical study with an investigational product (IP) during the last 3 weeks

Cannot have received: anti-cancer therapy

Receipt of the last dose of anti-cancer therapy (chemotherapy, immunotherapy, endocrine therapy, targeted therapy, biologic therapy, tumor embolization, monoclonal antibodies, other investigational agent) 28 days prior to the first dose of study drug

Lab requirements

Blood counts

Kidney function

Liver function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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