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OncoMatch/Clinical Trials/NCT04322890

Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation

Is NCT04322890 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments for non small cell lung cancer.

Phase 2RecruitingHunan Province Tumor HospitalNCT04322890Data as of May 2026

Treatment: Osimertinib · Alectinib 150 MG · Crizotinib 250 MG · Savolitinib, Crizotinib. · ChemotherapyThe purpose of this study is to assess the Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation.

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Extracted eligibility criteria

Cancer type

Small Cell Lung Cancer

Biomarker criteria

Required: EGFR oncogenic mutation

Oncogenic mutations confirmed by an accredited local laboratory, including EGFR, ALK, ROS1 etc.

Required: ALK oncogenic mutation

Oncogenic mutations confirmed by an accredited local laboratory, including EGFR, ALK, ROS1 etc.

Required: ROS1 oncogenic mutation

Oncogenic mutations confirmed by an accredited local laboratory, including EGFR, ALK, ROS1 etc.

Required: MET oncogenic mutation

Oncogenic mutations confirmed by an accredited local laboratory, including EGFR, ALK, ROS1 etc.

Disease stage

Required: Stage IV

Metastatic disease required

Performance status

ECOG 0–1(Restricted strenuous activity)

Lab requirements

Blood counts

Adequate bone marrow hematopoiesis

Kidney function

Adequate organ function

Liver function

Adequate organ function

Adequate bone marrow hematopoiesis and organ function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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