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OncoMatch/Clinical Trials/NCT04301765

Improving Cancer-related Fatigue, Sexual Dysfunction and Quality of Life in Older Men With Cancer and Androgen Deficiency

Is NCT04301765 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies testosterone 1.62% gel for hypogonadism, male.

Phase 2RecruitingSeattle Institute for Biomedical and Clinical ResearchNCT04301765Data as of May 2026

Treatment: testosterone 1.62% gelThis is a large randomized, double-blind, placebo-controlled trial to determine the efficacy of testosterone replacement on cancer-related fatigue in older men with solid or hematologic (blood) cancer who report fatigue and have low testosterone levels.

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Extracted eligibility criteria

Prior therapy

Must have received: chemotherapy

have received or are receiving chemo- and/or radiation therapy

Must have received: radiation therapy

have received or are receiving chemo- and/or radiation therapy

Cannot have received: anabolic agents (testosterone, DHEA, growth hormone)

Use of anabolic agents (testosterone, DHEA, growth hormone) within the past 6 months

Lab requirements

Blood counts

Hematocrit >48% [excluded]

Hematocrit >48%, serum creatinine >2.5 mg/dL

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Georgia Cancer Center at Augusta University · Augusta, Georgia
  • Brigham and Women's Hospital · Boston, Massachusetts
  • Veterans Affairs Puget Sound Health Care System · Seattle, Washington

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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