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OncoMatch/Clinical Trials/NCT04301765

Improving Cancer-related Fatigue, Sexual Dysfunction and Quality of Life in Older Men With Cancer and Androgen Deficiency

Is NCT04301765 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies testosterone 1.62% gel for hypogonadism, male.

Phase 2RecruitingSeattle Institute for Biomedical and Clinical ResearchNCT04301765Data as of Jun 2026

Treatment: testosterone 1.62% gelThis is a large randomized, double-blind, placebo-controlled trial to determine the efficacy of testosterone replacement on cancer-related fatigue in older men with solid or hematologic (blood) cancer who report fatigue and have low testosterone levels.

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Extracted eligibility criteria

Treatments studied

Other

testosterone 1.62% gel

Demographics

Ages ≥ 55
Male only

Prior therapy

Must have received: chemotherapy

have received or are receiving chemo- and/or radiation therapy

Must have received: radiation therapy

have received or are receiving chemo- and/or radiation therapy

Cannot have received: anabolic agents (testosterone, DHEA, growth hormone)

Use of anabolic agents (testosterone, DHEA, growth hormone) within the past 6 months

Lab requirements

Blood counts

Hematocrit >48% [excluded]

Hematocrit >48%, serum creatinine >2.5 mg/dL

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Georgia Cancer Center at Augusta University · Augusta, Georgia
  • Brigham and Women's Hospital · Boston, Massachusetts
  • Veterans Affairs Puget Sound Health Care System · Seattle, Washington

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT04301765 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior anabolic agents disqualifies patients from enrollment.

Is this trial open to female patients?

No. This trial enrolls male patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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