OncoMatch

OncoMatch/Clinical Trials/NCT04278287

Chemoradiotherapy in Unresectable Esophageal Cancer

Is NCT04278287 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1/2 trial studies multiple treatments including Albumin-Bound Paclitaxel and Cisplatin for esophageal cancer.

Phase 1/2RecruitingCancer Institute and Hospital, Chinese Academy of Medical SciencesNCT04278287Data as of Jun 2026Location: China

Treatment: Albumin-Bound Paclitaxel · CisplatinThis phase I/II clinical study is designed to evaluate the 1 year local tumor control rate of chemoradiotherapy using albumin-bound paclitaxel and cisplatin in unresectable esophageal squamous cell carcinomas based on Nutritional Risk Screening NRS2002.

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Extracted eligibility criteria

Treatments studied

Chemotherapy

Albumin-Bound PaclitaxelCisplatin

Cancer type

Esophageal Carcinoma

Tumor Agnostic

Disease stage

Required: Stage T3N1M0-1B, T4N0-1M0-1B

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 75

Lab requirements

Blood counts

hemoglobin >= 100g/l; leukocytes >= 4,000 g/l; neutrophil >= 2,000 g/l; platelets >= 100,000/mm3

Kidney function

creatinine <= 1.5x uln or ccr >= 60 ml/min

Liver function

ast/alt <= 2.5x uln; total bilirubin <= 1.5x uln

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT04278287 currently recruiting?

Yes, this trial is currently recruiting patients.

What disease stage is eligible?

Stage T3N1M0-1B or T4N0-1M0-1B is required.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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