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OncoMatch/Clinical Trials/NCT04242017

Long-term Better Than Short-term ADT With Salvage RT

Is NCT04242017 recruiting? Yes, currently enrolling (May 2026). This Phase 2/3 trial studies Triptoreline for prostate cancer.

Phase 2/3RecruitingUniversitaire Ziekenhuizen KU LeuvenNCT04242017Data as of May 2026

Treatment: TriptorelineA randomized, multicenter, prospective PHASE II trial to assess the effect of short- versus long-term adjuvant ADT with high dose salvage radiotherapy on distant metastasis free survival in case of biochemical relapse (BR) after radical prostatectomy.

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Extracted eligibility criteria

Cancer type

Prostate Cancer

Disease stage

Excluded: Stage PN1, M1A-C

All patients have to be pN0. Presence of pN1 disease at original surgical specimen [excluded]. Presence of distant metastasis at time of referral (M1a-c) [excluded].

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Must have received: radical prostatectomy

treated with RP

Must have received: extended pelvic lymph node dissection

treated with ... ePLND

Cannot have received: radiation therapy

Exception: previous RT making new RT impossible (overlapping treatment fields)

Previous RT making new RT impossible (overlapping treatment fields) [excluded].

Cannot have received: androgen deprivation therapy

Active treatment with ADT ... [excluded].

Cannot have received: PSA modulating drugs (finasteride, dutasteride, high-dose corticoids)

Active treatment with ... PSA modulating drugs (finasteride, dutasteride, high-dose corticoids…) [excluded].

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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