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OncoMatch/Clinical Trials/NCT04214990

Aspirin Use for Gastric Cancer Prevention in the Early Gastric Cancer Patients

Is NCT04214990 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies Aspirin 100mg for aspirin.

Phase 3RecruitingNational Cancer Center, KoreaNCT04214990Data as of May 2026

Treatment: Aspirin 100mgThis study aimed to investigate the effect of low-dose (100 mg) asprin on the prevention of gastric cancer in the early gastric cancer patients with negative H. pylori status who underwent endoscopic submucosal dissection.

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Extracted eligibility criteria

Cancer type

Gastric Cancer

Disease stage

Required: Stage CATEGORY 4, CATEGORY 5 (Vienna classification of gastrointestinal epithelial neoplasia)

Grade: high-grade (Vienna classification)

category 4 [non-invasive high grade neoplasm] or category 5 [invasive neoplasia] according to the Vienna classification

Prior therapy

Must have received: endoscopic resection

who underwent endoscopic resection for high-grade adenoma or early gastric cancer

Cannot have received: gastrectomy

Previous gastrectomy history

Cannot have received: aspirin (secondary prevention of cardiovascular/cerebrovascular disease)

Patients who received aspirin for the secondary prevention of cardiovascular diseases or cerebrovascular diseases

Cannot have received: regular aspirin use

Regular aspirin uses (more than 3 times a week) with 2 months before screening visit

Cannot have received: anticoagulant or antiplatelet drugs

Patients who used anticoagulants or antiplatelet drugs for therapeutic purpose

Cannot have received: non-curative resection

Non-curative resection of early gastric cancer after endoscopic resection

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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