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OncoMatch/Clinical Trials/NCT04197297

Brain Imaging Biomarkers in Patients With Brain Metastasis

Is NCT04197297 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies non-drug interventions for brain metastases, adult.

Phase 2RecruitingUniversity Health Network, TorontoNCT04197297Data as of May 2026

A biomarker is a measurable indicator of the severity or presence of some disease state. In this study, brain metastases patients who will be receiving radiation treatment, will undergo CT (Computed Tomography) and MRI (Magnetic Resonance Imaging) scans prior to and after radiation treatment to measure these biomarkers. This is a single-center phase II study to validate the predictive abilities of biomarkers, in terms of determining how patients will respond to radiation treatment.

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Extracted eligibility criteria

Disease stage

Metastatic disease required

Prior therapy

Cannot have received: whole brain radiotherapy

Previous Whole Brain Radiotherapy

Cannot have received: radiosurgery to the index lesion

Previous radiosurgery to the index lesion

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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