OncoMatch/Clinical Trials/NCT04191460

Fluorescence-guided Surgery Using cRGD-ZW800-1 in Oral Cancer

Is NCT04191460 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies cRGD-ZW800-1. for squamous cell carcinoma of the head and neck.

Phase 2RecruitingErasmus Medical CenterNCT04191460Data as of May 2026

Treatment: cRGD-ZW800-1. — This is a two-staged clinical trial to investigate the feasibility of intraoperative Fluorescence Imaging (FLI) to adequately assess tumor margins in patients with oral cancer using cRGD-ZW800-1.

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Extracted eligibility criteria

Cancer type

Head and Neck Squamous Cell Carcinoma

Prior therapy

No prior treatment (treatment-naive required)

Cannot have received: surgery

Previous surgery ... to the oral cavity

Cannot have received: chemotherapy

Previous ... chemotherapy ... to the oral cavity

Cannot have received: radiotherapy

Previous ... radiotherapy to the oral cavity

Lab requirements

Kidney function

egfr >= 60

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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