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OncoMatch/Clinical Trials/NCT04191460

Fluorescence-guided Surgery Using cRGD-ZW800-1 in Oral Cancer

Is NCT04191460 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies cRGD-ZW800-1. for squamous cell carcinoma of the head and neck.

Phase 2RecruitingErasmus Medical CenterNCT04191460Data as of Jun 2026Location: Netherlands

Treatment: cRGD-ZW800-1.This is a two-staged clinical trial to investigate the feasibility of intraoperative Fluorescence Imaging (FLI) to adequately assess tumor margins in patients with oral cancer using cRGD-ZW800-1.

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Extracted eligibility criteria

Treatments studied

Other

cRGD-ZW800-1.

Cancer type

Head and Neck Squamous Cell Carcinoma

Prior therapy

No prior treatment (treatment-naive required)

Cannot have received: surgery

Previous surgery ... to the oral cavity

Cannot have received: chemotherapy

Previous ... chemotherapy ... to the oral cavity

Cannot have received: radiotherapy

Previous ... radiotherapy to the oral cavity

Lab requirements

Kidney function

egfr >= 60

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT04191460 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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