OncoMatch/Clinical Trials/NCT04166006
A Phase II Study on Adjuvant Vaccination with Dendritic Cells Loaded with Autologous Tumor Homogenate in Resected Stage IV Rare Cancers.
Is NCT04166006 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments including Autologous DC vaccine and Interleukin-2 for head neck tumors.
Treatment: Autologous DC vaccine · Interleukin-2 — Single-arm, monocentric trial to assess safety and immunological efficacy of adjuvant vaccination with autologous dendritic cells loaded with autologous tumour homogenate after curative resection for stage IV rare cancers (In Head/Neck tumors (H\&N), NEuroendocrine Tumors (NET) and Soft Tissue Sarcomas (STS).
Check if I qualifyExtracted eligibility criteria
Treatments studied
Other
Cancer type
Neuroendocrine Tumor
Sarcoma
Disease stage
Required: Stage IV
Performance status
ECOG 0–1(Restricted strenuous activity)
Prior therapy
Must have received: surgery — radical intent
surgically treated with radical intent
Lab requirements
Blood counts
Haemoglobin >10 g/dl; WBC ≥3000/μl; ANC ≥1500/μl; platelets ≥75000/μl
Kidney function
serum creatinine <1.5x upper institutional reference level
Liver function
AST and ALT <3x upper institutional reference level; total bilirubin <1.5x upper institutional reference level
Cardiac function
Patients aged 70 years or older must have left ventricular ejection fraction not lower than 55% as assessed by echocardiography
Haemoglobin >10 g/dl; White blood cells ≥3000/μl; Absolute neutrophil count ≥1500/μl; Platelets≥75000/μl; AST and ALT <3x upper institutional reference level; Total bilirubin <1.5x upper institutional reference level; Serum creatinine <1.5x upper institutional reference level. Patients aged 70 years or older must have left ventricular ejection fraction not lower than 55% as assessed by echocardiography.
Structured fields extracted by AI. May contain errors — verify against the official protocol.
Frequently asked questions
Is NCT04166006 currently recruiting?
Yes, this trial is currently recruiting patients.
Is prior treatment required for enrollment?
Yes. Patients must have previously received surgery.
What disease stage is eligible?
Stage IV is required.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualifyRelated pages