OncoMatch

OncoMatch/Clinical Trials/NCT04136782

Albumin-bound Paclitaxel and Carboplatin Versus Epirubicin and Docetaxel for Triple-negative Breast Cancer

Is NCT04136782 recruiting? Yes, currently enrolling (Jun 2026). This Phase 4 trial studies multiple treatments including Albumin-bound paclitaxel combined with carboplatin and Epirubicin combined with docetaxel for breast cancer.

Phase 4RecruitingShengjing HospitalNCT04136782Data as of Jun 2026Location: China

Treatment: Albumin-bound paclitaxel combined with carboplatin · Epirubicin combined with docetaxelTo investigate the efficacy of albumin-bound paclitaxel combined with carboplatin versus epirubicin combined with docetaxel as neoadjuvant therapy for triple-negative breast cancer.

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Extracted eligibility criteria

Treatments studied

Chemotherapy

Albumin-bound paclitaxel combined with carboplatin

Other

Epirubicin combined with docetaxel

Cancer type

Breast Carcinoma

Biomarker criteria

Required: HER2 (ERBB2) negative (negative)

Required: ESR1 negative (negative)

Required: PR (PGR) negative (negative)

Disease stage

Required: Stage II, III

Excluded: Stage IV

Demographics

Ages ≤ 70
Female only

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: antineoplastic therapy

those who have received antineoplastic therapy

Cannot have received: neoadjuvant chemotherapy

Exception: patients who fail in 2 cycles of neoadjuvant chemotherapy and switch to other regimens or terminate chemotherapy

those who have received neoadjuvant chemotherapy but fail in 2 cycles of neoadjuvant chemotherapy and switch to other regimens or terminate chemotherapy

Lab requirements

Blood counts

normal routine blood test results

Kidney function

normal kidney function

Liver function

normal liver function

Cardiac function

near normal electrocardiographic manifestations

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT04136782 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

Does this trial require ERBB2?

Yes, ERBB2 negative is a required biomarker for enrollment.

Does this trial require ESR1?

Yes, ESR1 negative is a required biomarker for enrollment.

Does this trial require PGR?

Yes, PGR negative is a required biomarker for enrollment.

What disease stage is eligible?

Stage II or III is required.

Is there an age limit?

Yes. Patients must be 70 years or younger.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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