OncoMatch/Clinical Trials/NCT04135664
Comparison of Esophagectomy and Chemoradiation for Patients With cN0-pT1b Stage Esophageal Squamous Cell Carcinoma
Is NCT04135664 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies chemoradiation for esophageal cancer.
Treatment: chemoradiation — The ad-ESD trial is phase III randomized trial to compare adjuvant esophagectomy and chemoradiation for patients with clinical stage N0 and pathological stage T1b squamous cell carcinoma (after endoscopic submucosal dissection).
Check if I qualifyExtracted eligibility criteria
Cancer type
Esophageal Carcinoma
Disease stage
Required: Stage CN0, PT1B
Clinical N0 stage diagnosed by imaging examinations. Pathological T1b stage confirmed by endoscopic submucosal dissection.
Performance status
ECOG 0–1(Restricted strenuous activity)
Prior therapy
Cannot have received: intervention treatment before endoscopic submucosal resection
Prior intervention treatment before endoscopic submucosal resection.
Cannot have received: intervention (surgery, chemoradiation, et al.) for other primary tumor disease
Prior intervention (surgery, chemoradiation, et al.) for other primary tumor disease.
Structured fields extracted by AI. May contain errors — verify against the official protocol.
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