OncoMatch

OncoMatch/Clinical Trials/NCT04098744

Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3)

Is NCT04098744 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Artesunate vaginal insert for cin 2/3.

Phase 2RecruitingFrantz Viral Therapeutics, LLCNCT04098744Data as of Jun 2026

Treatment: Artesunate vaginal insertThis is a phase II double blind, placebo-controlled, randomized study of Artesunate vaginal inserts for the treatment of women who have cervical high grade intraepithelial neoplasia (CIN2/3).

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Extracted eligibility criteria

Treatments studied

Other

Artesunate vaginal insert

Biomarker criteria

Required: HPV any genotype

Any HPV genotype detectable by DNA test/HPV genotyping

Disease stage

Required: Stage CIN2, CIN3, CIN2/3

Excluded: Stage CERVICAL ADENOCARCINOMA IN SITU

Grade: high grade

cervical high grade squamous intraepithelial lesions (CIN2, CIN3, or CIN2/3)

Demographics

Ages 25–100
Female only

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Florida Gynecologic Oncology · Fort Myers, Florida
  • University of Michigan · Ann Arbor, Michigan
  • Cleveland Clinic Fairview Hospital · Cleveland, Ohio
  • Cleveland Clinic Foundation · Cleveland, Ohio
  • Hillcrest Hospital · Mayfield Heights, Ohio

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT04098744 currently recruiting?

Yes, this trial is currently recruiting patients.

Does this trial require HPV?

Yes, HPV any genotype is a required biomarker for enrollment.

What disease stage is eligible?

Stage CIN2 or CIN3 or CIN2/3 is required.

Is there an age limit?

Yes. Patients must be 100 years or younger and at least 25 years old.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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