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OncoMatch/Clinical Trials/NCT04085887

Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures

Is NCT04085887 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1/2 trial studies multiple treatments including Panitumumab-IRDye800 and Pinpoint-IR9000 endoscopic/handheld device for brain tumor.

Phase 1/2RecruitingStanford UniversityNCT04085887Data as of Jun 2026

Treatment: Panitumumab-IRDye800 · Pinpoint-IR9000 endoscopic/handheld device · Explorer Air camera · PDE-NEO-IIThe objective of the study is to assess safety of panitumumab-IRDye800 in pediatric patients undergoing brain surgery to remove suspected tumors.

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Extracted eligibility criteria

Treatments studied

Other

Panitumumab-IRDye800Pinpoint-IR9000 endoscopic/handheld deviceExplorer Air cameraPDE-NEO-II

Cancer type

Glioblastoma

Demographics

Ages 0–25

Prior therapy

Cannot have received: investigational drug

Received an investigational drug within 30 days prior to first dose of Panitumumab IRDye800

Lab requirements

Blood counts

Magnesium, potassium and calcium < the lower limit of normal per institution normal lab values [excluded]

Kidney function

Serum creatinine > 1.5 times upper reference range [excluded]

Cardiac function

Myocardial infarction (MI); cerebrovascular accident (CVA); uncontrolled congestive heart failure (CHF); unstable angina within 6 months prior to enrollment; Evidence of QTc prolongation on pretreatment ECG (greater than 440 ms in children 1-8 years or 8-18 year old males or greater than 460 ms in infants up to 1 year or 8-18 year old females); Subjects receiving Class IA (quinidine, procainamide) or Class III (dofetilide, amiodarone, sotalol) antiarrhythmic agents.

Myocardial infarction (MI); cerebrovascular accident (CVA); uncontrolled congestive heart failure (CHF); significant liver disease; or unstable angina within 6 months prior to enrollment Evidence of QTc prolongation on pretreatment ECG (greater than 440 ms in children 1 8 years or 8 to 18 year old males or greater than 460 ms in infants up to 1 year or 8 to 18 year old females) Magnesium, potassium and calcium < the lower limit of normal per institution normal lab values Serum creatinine > 1.5 times upper reference range Subjects receiving Class IA (quinidine, procainamide) or Class III (dofetilide, amiodarone, sotalol) antiarrhythmic agents.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Stanford Cancer Center · Stanford, California

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Frequently asked questions

Is NCT04085887 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior investigational drug disqualifies patients from enrollment.

Is there an age limit?

Yes. Patients must be 25 years or younger and at least 0 years old.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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Related pages

Glioblastoma trials