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OncoMatch/Clinical Trials/NCT04038619

Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients

Is NCT04038619 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1 trial studies Loperamide for colitis.

Phase 1RecruitingM.D. Anderson Cancer CenterNCT04038619Data as of Jun 2026

Treatment: LoperamideThis trial studies how well fecal microbiota transplantation works in treating diarrhea or colitis (inflammation of the intestines) that is caused by certain types of medications (called immune-checkpoint inhibitors) in patients with genitourinary cancer. Fecal microbiota transplantation may effectively reduce the incidence of immune checkpoint inhibitor-induced diarrhea/colitis.

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Extracted eligibility criteria

Treatments studied

Other

Loperamide

Cancer type

Melanoma

Non-Small Cell Lung Carcinoma

Small Cell Lung Cancer

Ovarian Cancer

Endometrial Cancer

Breast Carcinoma

Cervical Cancer

Prior therapy

Must have received: checkpoint inhibitor

Treatment with any ICPI agent(s)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • M D Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites.

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Frequently asked questions

Is NCT04038619 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received checkpoint inhibitor.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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