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OncoMatch/Clinical Trials/NCT04038619

Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients

Is NCT04038619 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies Loperamide for colitis.

Phase 1RecruitingM.D. Anderson Cancer CenterNCT04038619Data as of May 2026

Treatment: LoperamideThis trial studies how well fecal microbiota transplantation works in treating diarrhea or colitis (inflammation of the intestines) that is caused by certain types of medications (called immune-checkpoint inhibitors) in patients with genitourinary cancer. Fecal microbiota transplantation may effectively reduce the incidence of immune checkpoint inhibitor-induced diarrhea/colitis.

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Extracted eligibility criteria

Cancer type

Melanoma

Non-Small Cell Lung Carcinoma

Ovarian Cancer

Endometrial Cancer

Breast Carcinoma

Cervical Cancer

Prior therapy

Must have received: checkpoint inhibitor

Treatment with any ICPI agent(s)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • M D Anderson Cancer Center · Houston, Texas

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