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OncoMatch/Clinical Trials/NCT03965234

Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases

Is NCT03965234 recruiting? Yes, currently enrolling (Sep 2026). This Phase 1/2 trial studies Cisplatin for metastatic bone sarcoma.

Phase 1/2RecruitingRoswell Park Cancer InstituteNCT03965234Data as of Sep 2026

Treatment: CisplatinThis phase I/II trial studies the side effects of pulmonary suffusion in controlling minimal residual disease in patients with sarcoma or colorectal carcinoma that has spread to the lungs. Pulmonary suffusion is a minimally invasive delivery of chemotherapeutic agents like cisplatin to lung tissues. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Pulmonary suffusion may also be useful in avoiding later use of drugs by vein that demonstrate no effect on tumors when delivered locally. The Phase 1 portion of the study has been completed.

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Extracted eligibility criteria

Treatments studied

Chemotherapy

Cisplatin

Cancer type

Sarcoma

Tumor Agnostic

Colorectal Cancer

Disease stage

Metastatic disease required

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Lab requirements

Blood counts

hemoglobin > 8.0 g/l; neutrophils > 1,500 ul; platelets >= 100,000 ul

Kidney function

creatinine clearance >= 30 ml/min

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Roswell Park Cancer Institute · Buffalo, New York

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Frequently asked questions

Is NCT03965234 currently recruiting?

Yes, this trial is currently recruiting patients.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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