OncoMatch/Clinical Trials/NCT03823534
Post-Op Pain Control for Prophylactic Intramedullary Nailing.
Is NCT03823534 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies multiple treatments for bone metastases.
Treatment: Ketorolac · Normal saline · Acetaminophen · Oxycodone Acetaminophen · Morphine · Hydrocodone/Acetaminophen · Oxycodone — Nationally, the opioid crisis has become a major epidemic with increasing mortality rates each year. Orthopedic surgeons routinely prescribe narcotics instead of NSAIDs for post-op pain control because of risk of delayed healing and nonunion due to NSAID use. Orthopedic oncology, however, has a unique subset of patients that undergo prophylactic placement of intramedullary femoral nails. Because no fracture is present, these patients do not rely on inflammatory healing factors, allowing for post-op NSAID use. This study sets out to determine the effect of post-op toradol use in addition to opioids compared to solely opioids in patients undergoing prophylactic nailing of the femur.
Check if I qualifyExtracted eligibility criteria
Cancer type
Non-Hodgkin Lymphoma
Multiple Myeloma
Lab requirements
Kidney function
No advanced renal impairment (eGFR<30mL/min)
History of advanced renal impairment (eGFR<30mL/min) [excluded]
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- Saint Louis University · St Louis, Missouri
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