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OncoMatch/Clinical Trials/NCT03808337

Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Original Site of Disease

Is NCT03808337 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Systemic Therapy/Standard of Care for triple negative breast cancer.

Phase 2RecruitingMemorial Sloan Kettering Cancer CenterNCT03808337Data as of May 2026

Treatment: Systemic Therapy/Standard of CareThis study is being done to determine if stereotactic body radiotherapy (SBRT) when delivered to all sites of disease in participants with 1-5 metastases will increase the length of time before participants' disease gets worse.

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Extracted eligibility criteria

Cancer type

Triple-Negative Breast Cancer

Breast Carcinoma

Small Cell Lung Cancer

Non-Small Cell Lung Carcinoma

Biomarker criteria

Required: ALK wild-type

Required: EGFR wild-type

Required: ROS1 wild-type

Allowed: ALK targetable molecular alteration

Allowed: EGFR targetable molecular alteration

Allowed: ROS1 targetable molecular alteration

Disease stage

Required: Stage IV, DE NOVO STAGE IV

Metastatic disease required

Metastatic disease detected on imaging and histologically confirmed

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Natera, Inc. (Data and Specimen Analysis Only) · San Carlos, California
  • Hartford Healthcare · Hartford, Connecticut
  • WCHN Norwalk Hospital - Data Collection · Norwalk, Connecticut
  • Baptist Alliance - McI · Miami, Florida
  • Memorial Sloan Kettering Basking Ridge · Basking Ridge, New Jersey

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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