OncoMatch/Clinical Trials/NCT03769766

Trial of Curcumin to Prevent Progression of Low-risk Prostate Cancer Under Active Surveillance

Is NCT03769766 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies Curcumin for prostate cancer.

Phase 3RecruitingUniversity of Texas Southwestern Medical CenterNCT03769766Data as of May 2026

Treatment: Curcumin — This is a prospective study to determine if the use of curcumin randomized against placebo will reduce cancer progression in patients with prostate cancer undergoing active surveillance.

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Extracted eligibility criteria

Cancer type

Prostate Cancer

Disease stage

Grade: ≤6 (gleason)

Prior therapy

No prior treatment (treatment-naive required)

Max 0 prior lines

Cannot have received: radiotherapy

Any previous prostate cancer treatment (radiotherapy, chemotherapy, hormonal therapy, oral glucocorticoids, GnRH analogues, prostatectomy)

Cannot have received: chemotherapy

Any previous prostate cancer treatment (radiotherapy, chemotherapy, hormonal therapy, oral glucocorticoids, GnRH analogues, prostatectomy)

Cannot have received: hormonal therapy

Any previous prostate cancer treatment (radiotherapy, chemotherapy, hormonal therapy, oral glucocorticoids, GnRH analogues, prostatectomy)

Cannot have received: oral glucocorticoids

Any previous prostate cancer treatment (radiotherapy, chemotherapy, hormonal therapy, oral glucocorticoids, GnRH analogues, prostatectomy)

Cannot have received: GnRH analogue

Any previous prostate cancer treatment (radiotherapy, chemotherapy, hormonal therapy, oral glucocorticoids, GnRH analogues, prostatectomy)

Cannot have received: surgery (prostatectomy)

Any previous prostate cancer treatment (radiotherapy, chemotherapy, hormonal therapy, oral glucocorticoids, GnRH analogues, prostatectomy)

Cannot have received: 5α-reductase inhibitor

Exception: use within 6 months of screening

Concurrent or previous use within 6 months of screening of any 5α-reductase inhibitor

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

UT Southwestern Medical Center · Dallas, Texas

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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