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OncoMatch/Clinical Trials/NCT03701581

4-aminopyridine Treatment for Nerve Injury

Is NCT03701581 recruiting? Yes, currently enrolling (May 2026). This Phase 2/3 trial studies 4-Aminopyridine for nerve injury.

Phase 2/3RecruitingJohn ElfarNCT03701581Data as of May 2026

Treatment: 4-AminopyridineTo evaluate the role of 4-aminopyridine (4-AP) on the course of recovery after peripheral nerve traction and/or crush injury. This study aims to test the hypothesis that 4-aminopyridine speeds the often slow and unpredictable recovery after peripheral nerve traction and/or crush injuries.

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Extracted eligibility criteria

Cancer type

Prostate Cancer

Disease stage

Required: Stage CT1C, CT2A, CT2B, CT2C (clinical TNM)

organ-confined, non-metastatic prostate cancer (stages cT1c-T2c)

Prior therapy

Cannot have received: neo-adjuvant therapy

Neo-adjuvant therapy prior to NSRP

Cannot have received: adjuvant therapy (radiation, androgen deprivation therapy)

Planned adjuvant therapy after NSRP based on specimen pathology and stage of prostate cancer (stage T3 or greater), positive lymph nodes or positive surgical margins

Lab requirements

Kidney function

gfr >= 60 ml/min

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of Arizona · Tucson, Arizona
  • University of Rochester · Rochester, New York

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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