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OncoMatch/Clinical Trials/NCT03659448

Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer

Is NCT03659448 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies SGM-101 for colorectal neoplasms.

Phase 3RecruitingSurgimabNCT03659448Data as of May 2026

Treatment: SGM-101The performance of SGM-101, an intraoperative imaging agent, will be compared to that of standard "white light" visualization during surgical resections of colorectal cancer.

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Extracted eligibility criteria

Cancer type

Colorectal Cancer

Disease stage

Required: Stage PERITONEAL METASTASIZED (clinical TNM)

primary cT4 colon cancer or primary cT3/4 rectal cancer, recurrent colorectal cancer or peritoneal metastasized colorectal cancer

Lab requirements

Blood counts

Absolute neutrophils counts below 1.5 x 10^9/L, Platelet count below 100 x 10^9/L, Hemoglobin below 4 mmol/L (females) or below 5 mmol/L (males) excluded

Kidney function

Serum creatinine above 1.5 times the ULN excluded

Liver function

Aspartate AminoTransferase, Alanine AminoTransferase, Gamma Glutamyl Transferase or Alkaline Phosphatase levels above 5 times the ULN excluded; Total bilirubin above 2 times the ULN excluded

Laboratory abnormalities defined as: Aspartate AminoTransferase, Alanine AminoTransferase, Gamma Glutamyl Transferase or Alkaline Phosphatase levels above 5 times the ULN or; Total bilirubin above 2 times the ULN or; Serum creatinine above 1.5 times the ULN or; Absolute neutrophils counts below 1.5 x 10^9/L or; Platelet count below 100 x 10^9/L or; Hemoglobin below 4 mmol/L (females) or below 5 mmol/l (males);

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • City of Hope National Medical Center · Duarte, California
  • Moores Cancer Center - UCSD Health · La Jolla, California
  • Cleveland Clinic Florida · Weston, Florida
  • Massachusetts General Hospital · Boston, Massachusetts
  • University of Massachusetts · Worcester, Massachusetts

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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