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OncoMatch/Clinical Trials/NCT03659448

Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer

Is NCT03659448 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies SGM-101 for colorectal neoplasms.

Phase 3RecruitingSurgimabNCT03659448Data as of Jun 2026Location: International · 4 countries

Treatment: SGM-101The performance of SGM-101, an intraoperative imaging agent, will be compared to that of standard "white light" visualization during surgical resections of colorectal cancer.

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Extracted eligibility criteria

Treatments studied

Other

SGM-101

Cancer type

Colorectal Cancer

Disease stage

Required: Stage PERITONEAL METASTASIZED (clinical TNM)

primary cT4 colon cancer or primary cT3/4 rectal cancer, recurrent colorectal cancer or peritoneal metastasized colorectal cancer

Lab requirements

Blood counts

Absolute neutrophils counts below 1.5 x 10^9/L, Platelet count below 100 x 10^9/L, Hemoglobin below 4 mmol/L (females) or below 5 mmol/L (males) excluded

Kidney function

Serum creatinine above 1.5 times the ULN excluded

Liver function

Aspartate AminoTransferase, Alanine AminoTransferase, Gamma Glutamyl Transferase or Alkaline Phosphatase levels above 5 times the ULN excluded; Total bilirubin above 2 times the ULN excluded

Laboratory abnormalities defined as: Aspartate AminoTransferase, Alanine AminoTransferase, Gamma Glutamyl Transferase or Alkaline Phosphatase levels above 5 times the ULN or; Total bilirubin above 2 times the ULN or; Serum creatinine above 1.5 times the ULN or; Absolute neutrophils counts below 1.5 x 10^9/L or; Platelet count below 100 x 10^9/L or; Hemoglobin below 4 mmol/L (females) or below 5 mmol/l (males);

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • City of Hope National Medical Center · Duarte, California
  • Moores Cancer Center - UCSD Health · La Jolla, California
  • Cleveland Clinic Florida · Weston, Florida
  • Massachusetts General Hospital · Boston, Massachusetts
  • University of Massachusetts · Worcester, Massachusetts

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT03659448 currently recruiting?

Yes, this trial is currently recruiting patients.

What disease stage is eligible?

Stage PERITONEAL METASTASIZED is required.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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