OncoMatch/Clinical Trials/NCT03557619
A Study to Assess the Effect of Venetoclax on Ethinyl Estradiol and Levonorgestrel in Female Participants With Different Hematological Malignancies
Is NCT03557619 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies multiple treatments including Venetoclax and ethinyl estradiol/levonorgestrel for hematologic malignancies.
Treatment: Venetoclax · ethinyl estradiol/levonorgestrel — A study to assess the effect of multiple doses of venetoclax on the pharmacokinetics of ethinyl estradiol and levonorgestrel in female participants with different hematological malignancies. Upon completion of this study, participants receiving clinical benefit in the opinion of the investigator and without any clinically significant evidence of disease progression with no access to venetoclax (not approved for the treated indication) may continue receiving venetoclax at the discretion of the investigator in a separate extension study.
Check if I qualifyExtracted eligibility criteria
Cancer type
Acute Myeloid Leukemia
Acute Lymphoblastic Leukemia
Non-Hodgkin Lymphoma
Multiple Myeloma
Myelodysplastic Syndrome
Chronic Lymphocytic Leukemia
Performance status
ECOG 0–2(Ambulatory, capable of self-care)
Lab requirements
Blood counts
adequate bone marrow function as described in the protocol
Kidney function
adequate renal function as described in the protocol
Liver function
adequate hepatic function as described in the protocol
adequate bone marrow, coagulation, renal and hepatic function as described in the protocol
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- Duplicate_Henry Ford Health System /ID# 209090 · Detroit, Michigan
- Dartmouth-Hitchcock Medical Center /ID# 169097 · Lebanon, New Hampshire
- Gabrail Cancer Center Research /ID# 207039 · Canton, Ohio
Showing up to 5 US sites. See all sites on ClinicalTrials.gov →
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