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OncoMatch/Clinical Trials/NCT03495427

PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men w/ High Decipher Test Scores

Is NCT03495427 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2/3 trial studies F-DCFPyL for prostate cancer.

Phase 2/3RecruitingH. Lee Moffitt Cancer Center and Research InstituteNCT03495427Data as of Jun 2026

Treatment: F-DCFPyLThis study will enroll 60 patients previously enrolled to MCC#18523, "A Validation Study on the Impact of Decipher® Testing on Treatment Recommendations in African-American and Non-African American Men with Prostate Cancer: (VANDAAM)" that had high risk Decipher test results (Decipher score \>0.45). Patients with a high genomic classifier (GC) score at diagnosis will be approached for formal consenting for PSMA-PET imaging at 2 years post treatment.

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Extracted eligibility criteria

Treatments studied

Other

F-DCFPyL

Cancer type

Prostate Cancer

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Male only

Prior therapy

Must have received: radical prostatectomy

Treated with radical prostatectomy (RP) or radiation therapy (RT) (+/- short-term androgen deprivation therapy (ADT)) with ≥2 years follow up

Must have received: radiation therapy

Treated with radical prostatectomy (RP) or radiation therapy (RT) (+/- short-term androgen deprivation therapy (ADT)) with ≥2 years follow up

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • H. Lee Moffitt Cancer Center and Research Institute · Tampa, Florida

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Frequently asked questions

Is NCT03495427 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received radical prostatectomy and radiation therapy.

Is this trial open to female patients?

No. This trial enrolls male patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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