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OncoMatch/Clinical Trials/NCT03463252

Value of LNG-IUS as Fertility-preserving Treatment of EAH and EC

Is NCT03463252 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2/3 trial studies multiple treatments including Progesterone and Mirena® for endometrial cancer.

Phase 2/3RecruitingWest China Second University HospitalNCT03463252Data as of Jun 2026Location: China

Treatment: Progesterone · Mirena® · GnRH agonistPrimary end points: This clinical trial is aimed to analyze the effectiveness of Levonorgestrel-Releasing Intrauterine System (LNG-IUS, Mirena®) in the fertility-sparing treatment of atypical endometrial hyperplasia and early endometrial carcinoma, including pathology response and pregnancy outcome. Second end points: To analyze the appearances of side-effects.

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Extracted eligibility criteria

Treatments studied

Other

ProgesteroneMirena®GnRH agonist

Cancer type

Endometrial Cancer

Biomarker criteria

Required: PR (PGR) positive (positive)

Disease stage

Required: Stage 1A

Grade: 1

Demographics

Ages ≤ 40
Female only

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT03463252 currently recruiting?

Yes, this trial is currently recruiting patients.

Does this trial require PGR?

Yes, PGR positive is a required biomarker for enrollment.

What disease stage is eligible?

Stage 1A is required.

Is there an age limit?

Yes. Patients must be 40 years or younger.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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