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OncoMatch/Clinical Trials/NCT03368651

The Impact on Survival of Neo-adjuvant Transarterial Chemoinfusion (TAI) for Patients With Hepatocellular Carcinoma And Portal Vein Tumor Thrombosis (PVTT) Who Underwent Hepatectomy : A Random, Controlled, Stage III Clinical Trial.

Is NCT03368651 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies non-drug interventions for hepatocellular carcinoma.

Phase 3RecruitingSun Yat-sen UniversityNCT03368651Data as of May 2026

To compare the impact on survival of neo-adjuvant TAI for patients with HCC and PVTT who underwent hepatectomy.

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Extracted eligibility criteria

Cancer type

Hepatocellular Carcinoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: any prior treatment (including interferon)

not previous treated for tumor; be treated before (interferon included)

Lab requirements

Blood counts

neutrophil count≥2.0×10^9/L; hemoglobin≥100g/L; platelet count≥75×10^9/L; PT≤upper limit of normal plus 4 seconds; INR≤2.2

Kidney function

serum creatine<1.5-times upper limit of normal

Liver function

serum albumin≥35g/L; total bilirubin<2-times upper limit of normal; ALT<3-times upper limit of normal; AST<3-times upper limit of normal

the lab test could meet: neutrophil count≥2.0×10^9/L; hemoglobin≥100g/L; platelet count≥75×10^9/L; serum albumin≥35g/L; total bilirubin<2-times upper limit of normal; ALT<3-times upper limit of normal; AST<3-times upper limit of normal; serum creatine<1.5-times upper limit of normal; PT≤upper limit of normal plus 4 seconds; INR≤2.2

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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