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OncoMatch/Clinical Trials/NCT03363373

Naxitamab for High-Risk Neuroblastoma Patients With Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone and/or Bone Marrow

Is NCT03363373 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies GM-CSF + Naxitamab for neuroblastoma.

Phase 2RecruitingY-mAbs TherapeuticsNCT03363373Data as of May 2026

Treatment: GM-CSF + NaxitamabChildren and adults diagnosed with high-risk neuroblastoma patients with primary refractory disease or incomplete response to salvage treatment in bone and/or bone marrow will be treated for up to 101 weeks with naxitamab and granulocyte-macrophage colony stimulating factor (GM-CSF). Patients will be followed for up to five years after first dose. Naxitamab, also known as hu3F8 is a humanised monoclonal antibody targeting GD2

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Extracted eligibility criteria

Cancer type

Neuroblastoma

Prior therapy

Cannot have received: systemic anti-cancer therapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of Florida · Gainesville, Florida
  • University of Chicago · Chicago, Illinois
  • Riley Hospital for Children · Indianapolis, Indiana
  • Memorial Sloan Kettering Cancer Center · New York, New York
  • Nationwide Children's Hospital · Columbus, Ohio

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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