OncoMatch

OncoMatch/Clinical Trials/NCT03351842

Surgery With or Without Chemotherapy for Stage I NSCLC With Micropapillary Component ≥ 20%

Is NCT03351842 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies cis Platinum/Carboplatin, Pemetrexed Disodium for chemotherapy, adjuvant.

Phase 2RecruitingShanghai Pulmonary Hospital, Shanghai, ChinaNCT03351842Data as of Jun 2026Location: China

Treatment: cis Platinum/Carboplatin, Pemetrexed DisodiumRandomized phase II trial aims to compare surgery with or without adjuvant chemotherapy in treating patients who are pathologically diagnosed as stage I lung adenocarcinoma with micropapillary component no less than 20%.

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Extracted eligibility criteria

Treatments studied

Chemotherapy

cis Platinum/Carboplatin, Pemetrexed Disodium

Cancer type

Non-Small Cell Lung Carcinoma

Disease stage

Required: Stage I

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages 19–70

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: chemotherapy

Cannot have received: radiation therapy

Lab requirements

Blood counts

granulocytes >= 1,800/ul; platelets >= 100,000/ul

Liver function

bilirubin < 1.5 mg/dl; sgot (ast) < 2.0 x uln

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT03351842 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

What disease stage is eligible?

Stage I is required.

Is there an age limit?

Yes. Patients must be 70 years or younger and at least 19 years old.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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