OncoMatch

OncoMatch/Clinical Trials/NCT03340506

Dabrafenib and/or Trametinib Rollover Study

Is NCT03340506 recruiting? Yes, currently enrolling (May 2026). This Phase 4 trial studies multiple treatments including dabrafenib and trametinib for melanoma.

Phase 4RecruitingNovartis PharmaceuticalsNCT03340506Data as of May 2026

Treatment: dabrafenib · trametinibThis study is to provide access for patients who are receiving treatment with dabrafenib and/or trametinib in a Novartis-sponsored Oncology Global Development, Global Medical Affairs or a former GSK-sponsored study who have fulfilled the requirements for the primary objective, and who are judged by the investigator as benefiting from continued treatment in the parent study as judged by the Investigator at the completion of the parent study.

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Extracted eligibility criteria

Cancer type

Melanoma

Small Cell Lung Cancer

Tumor Agnostic

Glioblastoma

Prior therapy

Must have received: dabrafenib and/or trametinib (dabrafenib, trametinib) — within a Novartis or former GSK sponsored study

currently receiving treatment with dabrafenib/trametinib monotherapy or combination within a Novartis or former GSK sponsored study

Cannot have received: dabrafenib and/or trametinib (dabrafenib, trametinib)

previously permanently discontinued from study treatment in the parent protocol

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Honor Health Research Institute · Scottsdale, Arizona
  • Honor Health Research Institute · Scottsdale, Arizona
  • National Institute Of Health · Bethesda, Maryland
  • James Cancer Hospital and Solove Research Institute Ohio State · Columbus, Ohio
  • Mary Crowley Cancer Research · Dallas, Texas

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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