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OncoMatch/Clinical Trials/NCT03180268

Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

Is NCT03180268 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies non-drug interventions for grade 2 meningioma.

Phase 3RecruitingNRG OncologyNCT03180268Data as of May 2026

This randomized phase III trial studies how well radiation therapy works compared with observation in treating patients with newly diagnosed grade II meningioma that has been completely removed by surgery. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors.

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Extracted eligibility criteria

Disease stage

Required: Stage WHO GRADE II (WHO 2016)

Grade: II (WHO 2016)

WHO grade II based upon pathology findings at the enrolling institution. WHO grade will be assigned according to WHO 2016 criteria

Performance status

ZUBROD 0–1

Prior therapy

Cannot have received: radiation therapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of Alabama at Birmingham Cancer Center · Birmingham, Alabama
  • Saint Joseph's Hospital and Medical Center · Phoenix, Arizona
  • Mayo Clinic Hospital in Arizona · Phoenix, Arizona
  • Mayo Clinic in Arizona · Scottsdale, Arizona
  • University of Arizona Cancer Center-Orange Grove Campus · Tucson, Arizona

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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