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OncoMatch/Clinical Trials/NCT02923011

Comparative Effectiveness of MRgFUS Versus CTgRFA for Osteoid Osteomas

Is NCT02923011 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies multiple treatments including MRgFUS and CTgRFA for osteoid osteoma.

Phase 3RecruitingMatthew BucknorNCT02923011Data as of May 2026

Treatment: MRgFUS · CTgRFAOsteoid osteomas are painful, benign bone tumors that occur most frequently in young males between ages 10 and 20 years. The goal of the proposed study is based on the premise that MRgFUS is noninferior to CT-guided radiofrequency ablation (CTgRFA), in terms of pain reduction following treatment of osteoid osteomas, and offers possible improvements with regards to 1) post-procedural pain, 2) clinical resource utilization, 3) patient experience, and/or 4) adverse events. The data from the current study would provide clinicians important information in deciding between treatment options for ablation of osteoid osteomas.

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Extracted eligibility criteria

Prior therapy

No prior treatment (treatment-naive required)

Cannot have received: interventional therapy for osteoid osteoma

No prior interventional therapy for the osteoid osteoma.

Lab requirements

Cardiac function

Patients with unstable cardiac status including: patients on anti-arrhythmic drugs, unstable angina pectoris, documented myocardial infarction within six months of protocol entry, congestive heart failure requiring medication (other than diuretic). Severe hypertension (diastolic BP > 100 on medication)

Patients with unstable cardiac status including: patients on anti-arrhythmic drugs, unstable angina pectoris, documented myocardial infarction within six months of protocol entry, congestive heart failure requiring medication (other than diuretic). Severe hypertension (diastolic BP > 100 on medication)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Stanford Medical Center · Palo Alto, California
  • UCSF Imaging Center · San Francisco, California
  • Mayo Clinic · Rochester, Minnesota

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