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OncoMatch/Clinical Trials/NCT02843945

Initial Feasibility Study to Treat Borderline Resectable Pancreatic Cancer With a Planar LDR Source

Is NCT02843945 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies Directional Brachytherapy Source Implant for pancreatic cancer.

Phase 1/2RecruitingCivaTech OncologyNCT02843945Data as of May 2026

Treatment: Directional Brachytherapy Source ImplantInitial study to evaluate local control and the preferred method of attachment of the CivaSheet in the setting of suspected close or positive margins at the time of surgical tumor removal.

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Extracted eligibility criteria

Cancer type

Pancreatic Cancer

Prior therapy

Must have received: chemoradiation (gemcitabine, nab-paclitaxel, FOLFIRINOX, capecitabine, 5-fluorouracil) — neoadjuvant

Patient Received neoadjuvant chemoradiation (4-10 weeks prior to surgery); Chemotherapy was administered for 2-6 cycles with any combination of the following agents: Gemcitabine + nb-paclitaxel, FOLFIRINOX; Neoadjuvant Chemoradiation was administered as IMRT or 3DCRT (up to 56 Gy), or SBRT (up to 36 Gy) with Pre-operative External beam dose (NCCN) up to 56 Gy (1.8-2.0 Gy per fractions) with concurrent gemcitabine, capecitabine, or infusional 5-fluorouracil

Cannot have received: radiation therapy

Exception: to the region for separate cancer

No prior radiation therapy to the region for separate cancer

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Tampa General Hospital · Tampa, Florida
  • Rush University Cancer Center · Chicago, Illinois
  • Advocate Christ Medical Center · Oak Lawn, Illinois
  • University Medical Center LSU · New Orleans, Louisiana
  • Fox Chase Cancer Center · Philadelphia, Pennsylvania

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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