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OncoMatch/Clinical Trials/NCT02710253

Salvage Radiation Therapy in Treating Patients With Metastatic Cancer That Has Progressed After Systemic Immunotherapy

Is NCT02710253 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies non-drug interventions for hematopoietic and lymphoid cell neoplasm.

Phase 2RecruitingM.D. Anderson Cancer CenterNCT02710253Data as of May 2026

This phase II trial studies the side effects and best dose of radiation therapy and to see how well it works in treating patients with cancer that has spread to other places in the body (metastatic) or has increased in size after being treated with immunotherapy. Giving radiation therapy may help to control the cancer after the disease has gotten worse after receiving immunotherapy in patients with cancer that has spread to the other places in the body.

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Extracted eligibility criteria

Cancer type

Acute Myeloid Leukemia

Acute Lymphoblastic Leukemia

Non-Hodgkin Lymphoma

Multiple Myeloma

Myelodysplastic Syndrome

Chronic Lymphocytic Leukemia

Tumor Agnostic

Disease stage

Metastatic disease required

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Min 1 prior line

Must have received: immunotherapy

Progressive disease via irRC on prior study or standard of care therapy utilizing an immunotherapy agent OR a clinical status that requires salvage radiation treatment

Cannot have received: radiation therapy

Exception: Allowed if high dose regions of prior and proposed radiation fields do not overlap, or overlap is only in low dose area

Has had prior radiation therapy within the past 3 months where the high dose area of the prior radiation would overlap with the high dose area of the intended radiation based on the judgment of the treating radiation oncologist.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • MD Anderson in The Woodlands · Conroe, Texas
  • M D Anderson Cancer Center · Houston, Texas
  • MD Anderson West Houston · Houston, Texas
  • MD Anderson League City · League City, Texas
  • MD Anderson in Sugar Land · Sugar Land, Texas

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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